5 Essential Elements For Demerol 1500 mg/30 ml interactions
5 Essential Elements For Demerol 1500 mg/30 ml interactions
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five.eighteen chance of Use in individuals with Atrial Flutter and also other Supraventricular Tachycardias DEMEROL Injection should be made use of with caution in people with atrial flutter and other supraventricular tachycardias as a result of a doable vagolytic motion which can make an important increase in the ventricular response price.
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The concomitant usage of anticholinergic medicine may improve chance of urinary retention and/or extreme constipation, which can produce paralytic ileus.
to scale back the chance of respiratory depression, appropriate dosing and titration of DEMEROL Injection are important [see Dosage and Administration (2.three)]. Overestimating the DEMEROL Injection dosage when changing people from A further opioid product can result in a fatal overdose with the first dose.
Neonates and younger infants may additionally be a lot more vulnerable to the effects, Primarily the respiratory depressant effects. If meperidine use is contemplated in neonates or youthful infants, any prospective advantages of the drug need to be weighed from the relative hazard in the patient.
Meperidine injection is used To ease average to critical soreness. it might be used before or all through medical procedures, or To alleviate suffering during labor or shipping and delivery.
Many acute pain circumstances (e.g., the pain that occurs with quite a few surgical methods or acute musculoskeletal accidents) require no various times of an opioid analgesic. Clinical guidelines on opioid prescribing for a few acute ache situations are offered.
The dose of DEMEROL Injection should be proportionately lowered (usually by twenty five to fifty percent) when administered concomitantly with phenothiazines and many other tranquilizers since they potentiate the motion of DEMEROL Injection.
suggest the two patients and caregivers about the challenges of respiratory despair and sedation when DEMEROL Injection is utilised with benzodiazepines or other CNS depressants (which include Alcoholic beverages and illicit medications). recommend individuals never to generate or operate hefty machinery right until the effects of concomitant use of the benzodiazepine or other CNS depressant have already been identified.
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Opioid analgesics, including DEMEROL Injection, can lengthen labor as a result of steps which temporarily decrease the power, duration, and frequency of uterine contractions. even so, this outcome just isn't dependable and may be offset by an increased fee of cervical dilation, which has a tendency to shorten labor. observe neonates exposed to opioid analgesics through labor for indications of extra sedation and respiratory depression.
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